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Gastroesophageal Reflux | © Cynthia Turner The lower esophageal sphincter opens more often than it should allowing stomach acid to travel up the lining of the esophagus and cause erosion. Damage by H. pylori bacteria to the protective lining of the duodenum results in an ulcer. For Nexium AstraZeneca “When It's More Than Just Heartburn” patient educational brochure.
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